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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
28.79
Human Site:
T1100
Identified Species:
45.24
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
T1100
G
S
R
H
P
C
I
T
K
T
F
F
G
D
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
T1100
G
S
R
H
P
C
I
T
K
T
F
F
G
D
D
Dog
Lupus familis
XP_531814
1283
145094
T1056
K
A
Y
C
V
L
V
T
G
P
N
M
G
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
T1098
G
S
R
H
P
C
I
T
K
T
F
F
G
D
D
Rat
Rattus norvegicus
XP_002726765
1361
151628
T1101
G
S
R
H
P
C
I
T
K
T
F
F
G
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
T1207
N
A
R
H
P
C
I
T
K
T
F
F
G
D
D
Frog
Xenopus laevis
NP_001089247
1340
149481
T1080
G
S
R
H
P
C
I
T
K
T
F
F
G
D
D
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
T1104
G
S
R
H
P
C
V
T
K
T
F
F
G
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
L967
N
M
G
G
K
S
T
L
M
R
E
V
G
L
L
Honey Bee
Apis mellifera
XP_392346
1120
127429
S897
L
A
T
E
N
F
A
S
F
M
I
L
T
G
P
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
P963
A
V
M
L
L
T
G
P
N
M
G
G
K
S
T
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
A1073
E
G
R
H
P
C
I
A
H
T
F
A
G
G
D
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
L1059
Q
V
C
L
A
V
I
L
A
Q
I
G
A
D
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
G1059
V
L
R
G
D
S
L
G
R
G
S
F
V
P
N
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
D1019
S
A
V
L
T
P
I
D
R
I
M
T
R
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
13.3
N.A.
100
100
N.A.
N.A.
86.6
100
93.3
N.A.
6.6
0
0
60
P-Site Similarity:
100
N.A.
100
26.6
N.A.
100
100
N.A.
N.A.
93.3
100
100
N.A.
6.6
13.3
0
60
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
27
0
0
7
0
7
7
7
0
0
7
7
0
0
% A
% Cys:
0
0
7
7
0
54
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
7
0
0
0
0
0
54
54
% D
% Glu:
7
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
7
0
54
54
0
0
0
% F
% Gly:
40
7
7
14
0
0
7
7
7
7
7
14
67
20
7
% G
% His:
0
0
0
54
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
60
0
0
7
14
0
0
0
0
% I
% Lys:
7
0
0
0
7
0
0
0
47
0
0
0
7
0
7
% K
% Leu:
7
7
0
20
7
7
7
14
0
0
0
7
0
14
7
% L
% Met:
0
7
7
0
0
0
0
0
7
14
7
7
0
0
0
% M
% Asn:
14
0
0
0
7
0
0
0
7
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
54
7
0
7
0
7
0
0
0
7
7
% P
% Gln:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
60
0
0
0
0
0
14
7
0
0
7
0
0
% R
% Ser:
7
40
0
0
0
14
0
7
0
0
7
0
0
7
0
% S
% Thr:
0
0
7
0
7
7
7
54
0
54
0
7
7
0
7
% T
% Val:
7
14
7
0
7
7
14
0
0
0
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _